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Innovation-driven trend shaping COVID-19 vaccine development in China

Frontiers of Medicine doi: 10.1007/s11684-023-1034-6

Abstract: Confronted with the coronavirus disease 2019 (COVID-19) pandemic, China has become an asset in tacklingprotein of SARS-CoV-2 or inactivated whole virus are a cornerstone of the public health response to COVID-19.we outline representative vaccines in multiple routes, while the merits and plights of the existing vaccine

Keywords： SARS-CoV-2     COVID-19 vaccine     vaccine development    

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SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 185-195 doi: 10.1007/s11684-021-0913-y

Abstract: its genomic sequence with the world, has greatly facilitated the development of coronavirus disease (COVID-19-19) diagnostics, drugs, and vaccines.develop more effective vaccines against SARS-CoV-2 variants and to understand the best prime-boost vaccinecombinations and immunization strategies to provide sufficient and sustainable immune protection against COVID-19.

Keywords： COVID-19     pandemics     SARS-CoV-2     vaccination    

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A review of the safety and efficacy of current COVID-19 vaccines

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 39-55 doi: 10.1007/s11684-021-0893-y

Abstract: Vaccination is the most effective and feasible way to contain the coronavirus disease 2019 (COVID-19)The rapid development of effective COVID-19 vaccines is an extraordinary achievement.study reviewed the efficacy/effectiveness, immunogenicity, and safety profile of the 12 most progressed COVID-19-19 vaccines and discussed the challenges and prospects of the vaccine-based approaches in a global crisiscoverage, strategies to address variants with immune escape capability, and surveillance of vaccine

Keywords： COVID-19     SARS-CoV-2     vaccine     safety     efficacy     effectiveness     immunogenicity    

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Effectiveness of inactivated COVID-19 vaccine against the severity of Omicron variant

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 576-580 doi: 10.1007/s11684-023-0991-0

Abstract: Effectiveness of inactivated COVID-19 vaccine against the severity of Omicron variant

Keywords： variant    

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Review on Drug Regulatory Science Promoting COVID-19 Vaccine Development in China Review

Zhiming Huang, Zhihao Fu, Junzhi Wang

Engineering 2022, Volume 10, Issue 3,   Pages 127-132 doi: 10.1016/j.eng.2022.01.001

Abstract: science, vaccines have played a major role in the prevention and control of coronavirus disease 2019 (COVID-19-19).This review summarizes the overall state of the vaccine industry, research and development (R&D)of COVID-19 vaccines in China, and the general state of regulatory science and supervision for vaccinesFurther, this review highlights how regulatory science has promoted the R&D of Chinese COVID-19 vaccines

Keywords： Regulatory science     COVID-19 vaccine     Vaccine industry    

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Early assessment of the safety and immunogenicity of a third dose (booster) of COVID-19 immunization

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 93-101 doi: 10.1007/s11684-021-0914-x

Abstract: SARS-CoV-2) via vaccination is essential to combat the current pandemic of coronavirus disease 2019 (COVID-19-19).It has been noticed that the strength of anti-COVID-19 vaccination-induced immunity fades over time,Here we report a pilot open-label trial of a third dose of BBIBP-CorV, an inactivated SARS-CoV-2 vaccineFurthermore, in an exploratory study, a newly developed recombinant protein vaccine, NVSI-06-08 (CHO

Keywords： COVID-19     SARS-CoV-2     vaccine     immunization     booster immunization    

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COVID-19 Vaccine Allocation: Modeling Health Outcomes and Equity Implications of Alternative Strategies Article

Maddalena Ferranna, Daniel Cadarette, David E. Bloom

Engineering 2021, Volume 7, Issue 7,   Pages 924-935 doi: 10.1016/j.eng.2021.03.014

Abstract:

Given the scarcity of safe and effective COVID-19 vaccines, a chief policy question is how to allocateThis paper evaluates COVID-19 vaccine prioritization strategies proposed to date, focusing on their statedlargest reduction in deaths is achieved by prioritizing older adults in most scenarios, even if the vaccinemotive that would support an allocation strategy attaching absolute priority to essential workers for a vaccine

Keywords： Vaccine allocation     COVID-19     Equity     SEIR model    

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Challenges in the Development of a Vaccine Against COVID-19

Wei Chen, Feng-Cai Zhu

Engineering 2020, Volume 6, Issue 10,   Pages 1067-1069 doi: 10.1016/j.eng.2020.08.012

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COVID-19: why not learn from the past?

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 776-781 doi: 10.1007/s11684-021-0883-0

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SARS-CoV-2 variants, immune escape, and countermeasures

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 196-207 doi: 10.1007/s11684-021-0906-x

Abstract: Coronavirus disease 2019 (COVID-19) has become a global pandemic disease.

Keywords： SARS-CoV-2     COVID-19     vaccine     immune escape     breakthrough     prevention    

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Repercussions of COVID-19 pandemic on solid waste generation and management strategies

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1407-5

Abstract:

• Implication of COVID-19 on medical waste and MSW generation is studied

Keywords： COVID-19     Medical waste     Personal protective equipment     Municipal solid waste     Waste management    

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Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: The coronavirus disease 2019 (COVID-19) has spread globally.Although mixed liver impairment has been reported in COVID-19 patients, the association of liver injurycaused by specific subtype especially chronic hepatitis B (CHB) with COVID-19 has not been elucidatedmulti-center, retrospective, and observational cohort study, 109 CHB and 327 non-CHB patients with COVID-19In conclusion, COVID-19 patients with CHB were more likely to develop into severe illness and die.

Keywords： COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

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Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 984-990 doi: 10.1007/s11684-022-0930-5

Abstract: NPIs) have been commonly deployed to prevent and control the spread of the coronavirus disease 2019 (COVID-19Hemagglutination inhibition was performed to test antibodies against four influenza vaccine strains.meta-analyses was adopted to compare the seroprevalence of influenza antibodies before and during the COVID-19-19 pandemic.meta-analysis showed that antibodies against A/H1N1pdm09 and A/H3N2 were significantly low in adults after the COVID-19

Keywords： influenza virus     seroprevalence     antibody     COVID-19     cross-sectional study    

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Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 562-575 doi: 10.1007/s11684-022-0977-3

Abstract: The Omicron family of SARS-CoV-2 variants are currently driving the COVID-19 pandemic.In particular, severe/critical cases of COVID-19 post BA.2.2 infection were associated with less pro-inflammatoryFurthermore, even though age was a critical risk factor of the severity of COVID-19 post BA.2.2 infection, vaccination-elicited protection against severe/critical COVID-19 reached 90.15% in

Keywords： SARS-CoV-2     COVID-19     host response     bronchoalveolar lavage fluid (BALF)    

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Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19-19 in Wuhan

Li Ni, Ling Zhou, Min Zhou, Jianping Zhao, Dao Wen Wang

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 210-214 doi: 10.1007/s11684-020-0757-x

Abstract: Here we report the first family case of coronavirus disease 2019 (COVID-19) confirmed in Wuhan and treatedcourse, and management of three cases from a family, suggests the expected therapeutic effects of SHL on COVID-19-19, and warrants further clinical trials.

Keywords： novel coronavirus (2019-nCoV)     COVID-19     Chinese traditional patent medicine     Shuanghuanglian oral liquid    

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Title Author Date Type Operation

Innovation-driven trend shaping COVID-19 vaccine development in China

Journal Article

SARS-CoV-2 vaccine research and immunization strategies for improved control of the COVID-19 pandemic

Journal Article

A review of the safety and efficacy of current COVID-19 vaccines

Journal Article

Effectiveness of inactivated COVID-19 vaccine against the severity of Omicron variant

Journal Article

Review on Drug Regulatory Science Promoting COVID-19 Vaccine Development in China

Zhiming Huang, Zhihao Fu, Junzhi Wang

Journal Article

Early assessment of the safety and immunogenicity of a third dose (booster) of COVID-19 immunization

Journal Article

COVID-19 Vaccine Allocation: Modeling Health Outcomes and Equity Implications of Alternative Strategies

Maddalena Ferranna, Daniel Cadarette, David E. Bloom

Journal Article

Challenges in the Development of a Vaccine Against COVID-19

Wei Chen, Feng-Cai Zhu

Journal Article

COVID-19: why not learn from the past?

Journal Article

SARS-CoV-2 variants, immune escape, and countermeasures

Journal Article

Repercussions of COVID-19 pandemic on solid waste generation and management strategies

Journal Article

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Journal Article

Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic

Journal Article

Host protection against Omicron BA.2.2 sublineages by prior vaccination in spring 2022 COVID-19 outbreak

Journal Article

Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19-19 in Wuhan

Li Ni, Ling Zhou, Min Zhou, Jianping Zhao, Dao Wen Wang

Journal Article